THE RELATIONSHIP OF WRONG LAXATIVE USE WITH CONSTIPATION AND EATING DISORDERS in vitro: EFFECT ON HEALTHY COLON EPITHELI

Objective: It is estimated that the use of wrong laxatives will increase probability developing an eating disorder by affecting in behavior and physiological digestion. Long-term known many to impair normal colonic function producing laxative dependence. In our study, it was aimed determine effect Folliculj sennae plant, which used for slimming purposes, on CCD-18Co (normal colon epithelium) cell line.
 Materials Methods: The plant. Its antiproliferative line determined MTT test.
 Results: According concentrations line, % viability activities were between 73 54 50% inhibitory concentration value (IC50) calculated as 47 ppm.
 Conclusion: thought a has negative CCD18-Co make important contribution health professionals raise awareness their patients about laxatives.